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总览 评价 邹玮 * ， 王加俊 ， 方二喜 ， 胡丹峰 （ 苏州大学电子信息学院，苏州 215006； ） 摘要： 介观荧光成像的迭代重建中需要求解大量的未知数，导致了很高的计算复杂度。通常情况下，传统的重建只利用一种波长的测量数据，从而影响了重建效率。本文
邹玮*， 王加俊， 方二喜， 胡丹峰
（
苏州大学电子信息学院，苏州 215006； ）
摘要：
介观荧光成像的迭代重建中需要求解大量的未知数，导致了很高的计算复杂度。通常情况下，传统的重建只利用一种波长的测量数据，从而影响了重建效率。本文提出了一种基于双波长测量的介观荧光重建方法。利用发射光和激发光两种波长的测量数据轮流进行迭代重建。此外，低分辨率重建的解作为高分辨率迭代重建的初始值，高分辨率重建基于自适应细化网格。仿真结果表明，本文所提出的算法可以大大提高重建速度，同时有效改善了重建质量。
关键词：
自适应；双波长；测量数据
ZOU Wei*， WANG Jiajun， FANG Erxi， HU Danfeng
（
School of Electronic and Information Engineering, Soochow University, Suzhou 215006； ）
Abstract：
The iterative reconstruction of mesoscopic fluorescence imaging involves a large number of unknowns, which leads to high computational complexity. Basically, measurements based on only one kind of wavelength are used for conventional reconstruction. However, that will limit the reconstruction efficiency. A mesoscopic fluorescent reconstruction algorithm based on double-wavelength measurements is proposed in this paper. The emission light and excitation light measurements are used in turn for iterative reconstruction. Furthermore, the solution based on the coarse grid is used as an initial guess for iterative reconstruction based on the higher resolution. The high-resolution reconstruction is based on the adaptively refined grid. Simulation results demonstrate that the proposed algorithm is able to greatly accelerate the reconstruction process with the improved reconstruction quality.
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