申皓^1，， 王玲^1，*， 李涤尘^1，， 靳忠民^1，， 蓝平衡^2，， 张涌泉^3，

（  1、西安交通大学机械制造系统工程国家重点实验室，西安，710049；       2、 英国利兹大学医学生物工程学院，利兹，LS2 9JT；       3、第四军医大学西京医院骨肿瘤科，西安，710032；  ）

摘要： 软骨修复作为一种关节治疗手段主要针对的是小面积的软骨损伤。用于软骨修复的材料当中，人工材料具有材料来源广的优点，并且不像软骨异体移植会带来免疫反应、伦理等一系列问题。但是现有的医用材料种类繁多，包括钛合金、钴铬钼、陶瓷、钽金属等等，如何选择合适的材料仍然是研究的重点。本文通过实验对比了陶瓷材料和钛合金作为植入物在对磨自然软骨时摩擦学性能上的区别，结果表明钛合金和自然软骨面的摩擦系数较大，并且软骨表面粗糙度的变化也比陶瓷对磨面软骨明显。同时采用有限元建模分析了不同模量植入物与自然骨软骨的界面接触力学，结果表明弹性模量较小的材料有利于减少应力屏蔽。
关键词： 摩擦；植入物；软骨；应力屏蔽

SHEN Hao^1,， WANG Ling^1,*， LI Dichen^1,， JIN Zhongmin^1,， LAN Pingheng^2,，ZHANG Yongquan^3,

（  1、State key laboratory for manufacturing system engineering, Xi'an jiaotong university, Xi'an, 710049；       2、Institute of Medical and Biological Engineering, University of Leeds, Leeds, LS2 9JT；       3、Department of Orthopedic Oncology, Xi-Jing Hospital, The Fourth Military Medical University,Xi'an,710032；  ）

Abstract： Cartilage repair is a conservative treatment for small-scale cartilage lesion compared with joint replacement. Artificial materials have the advantage of spread sources. The implants consisting of artificial materials will never bring those problems just like immune response and ethical issues caused by cartilage transplantation. The existing biomaterials cover titanium alloy, CoCrMo alloy, ceramic, and tantalum. The content of this research compares the tribological properties of ceramic and titanium alloy by experimental approach when used for implants, the results show that the friction factor of titanium alloy and cartilage surface is higher and the cartilage roughness varies much more distinctly. Finite element simulation is used to analysis the contact mechanics of articular cartilage and implants. The results indicate that titanium alloy with low elastic modulus can decrease stress shielding compared with the higher one.
Keywords： Friction; Implants; Cartilage; Stress shielding

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